| 1 | MR | | Novak Djoković | 36 | SRB | 9990 | | |
| 10 | 3 | | Grigor Dimitrov | 32 | BUL | 3560 | | -80 | Madrid R64 | | 3600 | 4550 |
| 20 | 17 | | Adrian Mannarino | 35 | FRA | 1875 | | | Madrid R64 | | 1915 | 2865 |
| 33 | 32 | | Jordan Thompson | 30 | AUS | 1191 | | -65 | Madrid R64 | | 1231 | 2181 |
| 38 | 6 | | Gaël Monfils | 37 | FRA | 1145 | +2 | +3 | | Sconfitta Madrid R128  | |
| 41 | 21 | | Jan Lennard Struff | 34 | GER | 1070 | -17 | -558 | Madrid R32 | | 1120 | 2020 |
| 49 | 44 | | Marcos Giron | 30 | USA | 980 | +2 | -15 | | Sconfitta Madrid R128 | |
| 51 | 31 | | Márton Fucsovics | 32 | HUN | 932 | +2 | -10 | | |
| 58 | 45 | | Yannick Hanfmann | 32 | GER | 848 | | -51 | | Sconfitta Madrid R128 | |
| 62 | 49 | | Roberto Carballés Baena | 31 | ESP | 826 | +6 | +5 | Madrid R64 | | 846 | 1796 |
Pubblicità |
| 63 | 23 | | Dušan Lajović | 33 | SRB | 811 | +2 | -35 | | Sconfitta Madrid R128 | |
| 65 | 21 | | Daniel Evans | 33 | GBR | 806 | +4 | -10 | | |
| 74 | 49 | | Federico Coria | 32 | ARG | 736 | +9 | +16 | | Sconfitta Qualif. Madrid T2 | |
| 76 | 1 | | Andy Murray | 36 | GBR | 735 | -19 | -175 | | |
| 81 | 58 | | Taro Daniel | 31 | JPN | 715 | +4 | -2 | | Sconfitta Madrid R64 | |
| 85 | 9 | | Roberto Bautista Agut | 36 | ESP | 703 | +1 | -5 | Madrid R64 | Sconfitta Qualif. Madrid T2 | Sconfitta Qualif. Madrid T2
Madrid R64 | 723 | 1673 |
| 86 | 14 | | Aslan Karatsev | 30 | RUS | 675 | -38 | -366 | | Sconfitta Madrid R128 | |
| 87 | 3 | | Stan Wawrinka | 39 | SUI | 672 | | -25 | | |
| 88 | 48 | | Constant Lestienne | 31 | FRA | 669 | +2 | +11 | | |
| 90 | 9 | | Fabio Fognini | 36 | ITA | 650 | +4 | | |
| 102 | 17 | | Albert Ramos Viñolas | 36 | ESP | 595 | +3 | +5 | | Qualif. Madrid V
Sconfitta Madrid R128 | |
| 110 | 46 | | James Duckworth | 32 | AUS | 570 | +3 | +11 | Shenzhen SF | | 592 | 623 |
| 112 | 7 | | David Goffin | 33 | BEL | 562 | -11 | -50 | | Sconfitta Qualif. Madrid T1 | |
| 113 | 49 | | Grégoire Barrère | 30 | FRA | 560 | -5 | -15 | | Sconfitta Qualif. Madrid T1 | |
| 115 | 7 | | Richard Gasquet | 37 | FRA | 550 | +1 | +5 | | Qualif. Madrid V
Sconfitta Madrid R128 | |
| 116 | 3 | | Dominic Thiem | 30 | AUT | 547 | -6 | -15 | | Sconfitta Qualif. Madrid T2 | |
| 122 | 55 | | Facundo Bagnis | 34 | ARG | 510 | +14 | +50 | | Qualif. Madrid V
Sconfitta Madrid R64 | |
| 131 | 39 | | Mikhail Kukushkin | 36 | KAZ | 476 | -2 | | | Sconfitta Qualif. Madrid T1 | |
| 132 | 39 | | Radu Albot | 34 | MDA | 468 | +1 | +3 | | Sconfitta Qualif. Madrid T2 | |
| 139 | 36 | | Pierre Hugues Herbert | 33 | FRA | 447 | +4 | | | Sconfitta Qualif. Madrid T1 | |
| 140 | 23 | | Damir Džumhur | 31 | BIH | 446 | +5 | +6 | Ostrava SF | | 468 | 499 |
| 142 | 8 | | Diego Schwartzman | 31 | ARG | 439 | | -10 | | Sconfitta Qualif. Madrid T1 | |
| 143 | 18 | | Benoît Paire | 34 | FRA | 432 | -3 | -19 | | |
| 145 | 93 | | Liam Broady | 30 | GBR | 423 | +5 | | |
| 159 | 80 | | Jozef Kovalík | 31 | SVK | 377 | +5 | -9 | | Sconfitta Roma R16 | |
| 160 | 53 | | Denis Kudla | 31 | USA | 370 | +2 | -19 | | Sconfitta Savannah R16 | |
| 162 | 64 | | Hugo Dellien | 30 | BOL | 366 | +11 | +22 | Roma SF | | 388 | 419 |
| 168 | 112 | | Marco Trungelliti | 34 | ARG | 355 | +1 | -11 | | |
| 171 | NMR
(176) | | Denis Yevseyev | 30 | KAZ | 341 | +13 | +8 | | Sconfitta Shenzhen QF | |
| 184 | 60 | | Stefano Travaglia | 32 | ITA | 324 | +12 | +16 | Roma SF | | 346 | 377 |
| 186 | 78 | | Yasutaka Uchiyama | 31 | JPN | 319 | -18 | -50 | | Sconfitta Shenzhen R32 | |
| 187 | 63 | | Jason Kubler | 30 | AUS | 316 | +1 | -10 | | |
| 189 | 85 | | Dennis Novak | 30 | AUT | 310 | +16 | +12 | | Sconfitta Ostrava QF | |
| 193 | 3 | | Milos Raonic | 33 | CAN | 305 | +6 | | |
| 199 | 160 | | Alexander Ritschard | 30 | SUI | 301 | +10 | +6 | Savannah SF | | 323 | 354 |
| 205 | 142 | | Joris De Loore | 31 | BEL | 293 | -14 | -30 | | |
| 210 | 187 | | Oriol Roca Batalla | 30 | ESP | 289 | -2 | -7 | | Sconfitta Roma R32 | |
| 223 | 203 | | Jules Marie | 32 | FRA | 270 | -10 | -19 | | Sconfitta Shenzhen R16 | |
| 225 | 10 | | Lucas Pouille | 30 | FRA | 263 | +1 | | | Sconfitta Qualif. Madrid T1 | |
| 230 | 108 | | Franco Agamenone | 31 | ITA | 258 | -10 | -17 | | Sconfitta Roma R16 | |
Pubblicità |
| 231 | 135 | | Antoine Escoffier | 32 | FRA | 258 | +5 | +6 | | Sconfitta Shenzhen R16 | |
| 236 | 125 | | Alex Bolt | 31 | AUS | 245 | +8 | +6 | | Sconfitta Shenzhen R16 | |
| 241 | 49 | | Illya Marchenko | 36 | UKR | 241 | -1 | -2 | | Sconfitta Shenzhen R32 | |
| 249 | 20 | | Guido Pella | 33 | ARG | 235 | -2 | | |
| 250 | 135 | | Mitchell Krueger | 30 | USA | 234 | -11 | -10 | | Sconfitta Savannah R16 | |
| 251 | 41 | | Tennys Sandgren | 32 | USA | 233 | +9 | +6 | | Sconfitta Savannah R16 | |
| 252 | 97 | | Kimmer Coppejans | 30 | BEL | 232 | -2 | | |
| 254 | 17 | | Bernard Tomic | 31 | AUS | 230 | +2 | | | Sconfitta Savannah R32 | |
| 257 | 21 | | Steve Johnson | 34 | USA | 227 | +2 | | |
| 261 | 159 | | Dimitar Kuzmanov | 30 | BUL | 219 | +4 | -4 | | Sconfitta Ostrava R32 | |
| 262 | 124 | | Federico Gaio | 32 | ITA | 219 | -8 | -11 | | |
| 269 | 140 | | Mathias Bourgue | 30 | FRA | 210 | +5 | | |
| 273 | 78 | | Renzo Olivo | 32 | ARG | 206 | +5 | | | Sconfitta Concepción R32 | |
| 277 | 177 | | Andrea Collarini | 32 | ARG | 199 | -7 | -17 | | |
| 278 | 181 | | Tristan Lamasine | 31 | FRA | 199 | +7 | | | Sconfitta Ostrava R32 | |
| 281 | 114 | | Jason Jung | 34 | TWN | 197 | -12 | -20 | | |
| 285 | 70 | | Guido Andreozzi | 32 | ARG | 194 | +2 | -4 | | Sconfitta Qualif. Ostrava T1 | |
| 288 | 28 | | João Sousa | 35 | POR | 189 | +9 | | |
| 293 | 35 | | Jiří Veselý | 30 | CZE | 185 | -10 | -16 | | Sconfitta Ostrava R32 | |
| 294 | 152 | | Luke Saville | 30 | AUS | 180 | -2 | -13 | | Sconfitta Shenzhen R32 | |
| 295 | 273 | | Sebastian Fanselow | 32 | GER | 180 | +8 | | |
| 297 | 284 | | Pedro Sakamoto | 30 | BRA | 178 | +8 | | |
| 300 | 40 | | Ilya Ivashka | 30 | BLR | 176 | | -10 | | |
| 302 | 8 | | John Isner | 39 | USA | 175 | +5 | | |
| 321 | 127 | | Lorenzo Giustino | 32 | ITA | 160 | +3 | | |
| 325 | 65 | | Egor Gerasimov | 31 | BLR | 158 | +7 | +2 | | Sconfitta Qualif. Shenzhen T2 | |
| 330 | 16 | | Marco Cecchinato | 31 | ITA | 156 | -42 | -41 | | Sconfitta Roma R32 | |
| 334 | 143 | | Hiroki Moriya | 33 | JPN | 155 | | | | Sconfitta Qualif. Shenzhen T2
Sconfitta Shenzhen R32 | |
| 336 | 200 | | Yan Bai | 34 | CHN | 153 | +4 | | |
| 341 | 50 | | Ričardas Berankis | 33 | LTU | 150 | -12 | -7 | | Qualif. Shenzhen V
Sconfitta Shenzhen R32 | |
| 342 | 271 | | Moez Echargui | 31 | TUN | 150 | -11 | -7 | | Sconfitta Qualif. Shenzhen T1 | |
| 343 | 221 | | Hernán Casanova | 30 | ARG | 150 | -7 | -5 | | Sconfitta Concepción R16 | |
| 349 | 84 | | Alessandro Giannessi | 33 | ITA | 146 | -34 | -21 | | |
| 352 | 4 | | Kei Nishikori | 34 | JPN | 143 | +6 | | |
| 355 | 65 | | Evgeny Donskoy | 33 | RUS | 143 | -36 | -18 | | Sconfitta Qualif. Shenzhen T1 | |
| 357 | 164 | | Riccardo Bonadio | 30 | ITA | 143 | -46 | -30 | | Sconfitta Qualif. Roma T1 | |
| 359 | 127 | | Facundo Mena | 31 | ARG | 141 | +47 | +21 | Concepción QF | Santiago del Cile V | Santiago del Cile V
Concepción QF | 147 | 183 |
| 360 | 33 | | Federico Delbonis | 33 | ARG | 140 | -5 | -4 | | |
| 365 | 130 | | Mohamed Safwat | 33 | EGY | 137 | -8 | -7 | | |
| 366 | 56 | | Marius Copil | 33 | ROU | 136 | +1 | | | Sconfitta Qualif. Roma T1 | |
| 370 | 314 | | Benjamin Lock | 31 | ZIM | 135 | +14 | +5 | | Sconfitta Mosquera SF | |
| 377 | 57 | | Gastão Elias | 33 | POR | 131 | +1 | | |
| 380 | 76 | | Salvatore Caruso | 31 | ITA | 130 | -9 | -5 | | |
| 392 | 303 | | Arthur Weber | 31 | FRA | 125 | +3 | -1 | | Sconfitta Qualif. Roma T1 | |
| 393 | 211 | | Roberto Cid Subervi | 30 | DOM | 125 | +4 | -1 | | Sconfitta Concepción R32 | |
| 417 | 134 | | Steven Diez | 33 | CAN | 111 | -3 | -6 | | |
| 422 | 1 | | Rafael Nadal | 37 | ESP | 105 | +90 | +30 | Madrid R64
(R128 ) | | 125 | 1075 |
| 433 | 329 | | Nick Chappell | 31 | USA | 103 | +5 | | |
| 435 | 36 | | Oscar Otte | 30 | GER | 102 | -45 | -25 | | |
| 451 | 39 | | Peter Gojowczyk | 34 | GER | 96 | -21 | -9 | | |
Pubblicità |
| 454 | 207 | | Daniel Dutra da Silva | 35 | BRA | 95 | +10 | +4 | | Sconfitta Concepción R16 | |
| 456 | 206 | | Matija Pecotić | 34 | CRO | 94 | +4 | +2 | | Sconfitta Qualif. Savannah T2 | |
| 460 | 161 | | Filip Peliwo | 30 | POL | 94 | -1 | +1 | | Sconfitta Monastir 16 R16
Sconfitta Nottingham QF | |
| 465 | 234 | | Maxime Chazal | 31 | FRA | 91 | +3 | +1 | | Dubrovnik V
Sconfitta Spalato QF | |
| 484 | 478 | | Yurii Dzhavakian | 30 | UKR | 86 | -6 | | |
| 496 | 68 | | Gerald Melzer | 33 | AUT | 81 | -2 | | | Sconfitta Qualif. Savannah T2 | |
| 499 | 78 | | Blaž Rola | 33 | SLO | 80 | -47 | -16 | | |
| 508 | 80 | | Norbert Gombos | 33 | SVK | 76 | -9 | -3 | | Qualif. Ostrava V
Sconfitta Ostrava R32 | |
| 512 | 193 | | Zhe Li | 37 | CHN | 75 | +1 | | |
| 523 | 160 | | Gonzalo Lama | 30 | CHI | 73 | -1 | | |
| 530 | 16 | | Nikoloz Basilashvili | 32 | GEO | 71 | +9 | +2 | | Sconfitta Qualif. Ostrava T2 | |
| 533 | 136 | | Alexey Vatutin | 31 | RUS | 70 | +19 | +3 | | Sconfitta Angers QF | |
| 539 | 106 | | Darian King | 32 | BAR | 68 | +4 | | |
| 541 | 62 | | Kenny de Schepper | 36 | FRA | 68 | +16 | +2 | | Sconfitta Azay Le Rideau QF | |
| 544 | 273 | | Peter Heller | 31 | GER | 67 | -4 | -2 | | |
| 547 | 371 | | Karue Sell | 30 | BRA | 66 | +8 | | |
| 549 | 273 | | Elmar Ejupovic | 31 | GER | 66 | | -2 | | |
| 560 | 206 | | Daniel Cox | 33 | GBR | 63 | -63 | -17 | | Sconfitta Nottingham R32 | |
| 565 | 290 | | Shintaro Imai | 30 | JPN | 62 | +15 | +1 | | Sconfitta Nottingham R16 | |
| 590 | 341 | | Wilson Leite | 32 | BRA | 59 | +3 | -1 | | Sconfitta Qualif. Concepción T1 | |
| 595 | 232 | | José Pereira | 33 | BRA | 58 | +38 | +6 | Concepción QF | Qualif. Concepción V | Qualif. Concepción V
Concepción QF | 64 | 100 |
| 599 | 393 | | Pawel Juszczak | 30 | POL | 57 | +16 | +2 | | Sconfitta Hammamet 7 QF | |
| 602 | 466 | | Christoph Negritu | 30 | GER | 57 | +5 | | | Sconfitta Adalia 16 R32 | |
| 617 | 188 | | Miljan Zekić | 35 | SRB | 54 | +1 | | |
| 620 | 5 | | Kevin Anderson | 37 | RSA | 53 | +3 | | |
| 622 | 25 | | Vasek Pospisil | 33 | CAN | 53 | +3 | | |
| 631 | 259 | | Shuichi Sekiguchi | 32 | JPN | 51 | +7 | | |
| 645 | 466 | | Jea Moon Lee | 30 | KOR | 49 | -82 | -16 | | |
| 654 | 279 | | Rubin Statham | 37 | NZL | 48 | +9 | | |
| 667 | 84 | | Henri Laaksonen | 32 | SUI | 46 | -7 | -2 | | |
| 671 | 12 | | Feliciano López | 42 | ESP | 45 | +1 | | |
| 682 | 50 | | Juan Ignacio Lóndero | 30 | ARG | 43 | +6 | | |
| 683 | 225 | | Karim Mohamed Maamoun | 33 | EGY | 43 | +7 | | |
| 684 | 197 | | Jeremy Jahn | 34 | GER | 43 | +7 | | |
| 688 | 78 | | Nicolás Kicker | 31 | ARG | 42 | -88 | -16 | | |
| 694 | 26 | | Filip Krajinović | 32 | SRB | 41 | -201 | -40 | | |
| 696 | 40 | | Thiemo de Bakker | 35 | NED | 41 | +6 | | |
| 698 | 74 | | Mirza Bašić | 32 | BIH | 41 | +13 | +2 | | Sconfitta Dubrovnik SF
Sconfitta Spalato R16 | |
| 712 | 24 | | Martin Kližan | 34 | SVK | 38 | +127 | +15 | | Telde 2 V
Sconfitta Santa Margherita 5 R32 | |
| 713 | 236 | | JiSung Nam | 30 | KOR | 38 | -39 | -7 | | |
| 720 | 182 | | Maximilian Neuchrist | 32 | AUT | 37 | | |
| 777 | 7 | | Fernando Verdasco | 40 | ESP | 29 | -2 | | |
| 790 | 90 | | Emilio Gómez | 32 | ECU | 28 | -176 | -27 | | Sconfitta Concepción R32 | |
| 793 | 469 | | Juan Sebastián Gómez | 32 | COL | 27 | +255 | +16 | Mosquera F | | 36 | 36 |
| 797 | 430 | | Sidharth Rawat | 31 | IND | 27 | +1 | | |
| 825 | 19 | | Pablo Cuevas | 38 | URU | 24 | +6 | | |
| 829 | 60 | | Tatsuma Ito | 35 | JPN | 24 | -64 | -7 | | |
| 834 | 150 | | João Domingues | 30 | POR | 24 | -16 | -2 | | |
| 838 | 660 | | Michael Zhu | 31 | USA | 24 | +11 | +1 | | Qualif. Sanxenxo V
Sconfitta Sanxenxo R16 | |
| 868 | 115 | | Mats Moraing | 31 | GER | 21 | | |
Pubblicità |
| 871 | 523 | | Mark Whitehouse | 30 | GBR | 21 | -12 | -1 | | |
| 875 | 25 | | Jérémy Chardy | 37 | FRA | 20 | -106 | -10 | | |
| 878 | 663 | | Calum Puttergill | 30 | AUS | 20 | +2 | | |
| 884 | 165 | | Aldin Šetkić | 36 | BIH | 20 | +20 | +1 | | Sconfitta Dubrovnik R32
Sconfitta Spalato R16 | |
| 893 | 328 | | Arjun Kadhe | 30 | IND | 19 | +5 | | |
| 911 | 363 | | Oscar Jose Gutierrez | 31 | BRA | 19 | +11 | +1 | | Sconfitta Telde 2 R16 | |
| 923 | 153 | | Andrea Arnaboldi | 36 | ITA | 17 | +5 | | |
| 939 | 33 | | John Millman | 34 | AUS | 16 | -3 | | |
| 957 | 264 | | Aleksandre Metreveli | 30 | GEO | 15 | +81 | +3 | | Sconfitta Adalia 15 SF | |
| 969 | 26 | | Lukáš Rosol | 38 | CZE | 14 | +5 | | |
| 1000 | 532 | | Maciej Rajski | 32 | POL | 13 | +1 | | |
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